Dr Gareth Nye | University of Chester

Senior Lecturer

Gareth is a lecturer of physiology at Chester Medical School and is programme leader for BMedSci Medical Science. Gareth has expertise in the physiology of pregnancy and specialises in maternal and fetal health particularly the condition known as fetal growth restriction. He is an active supporter of student wellbeing and also a qualified mental health first aider.

Gareth started his career in academia by studying for a BSc in Physiology at The University of Liverpool progressing through to a PhD in pathophysiology.

Gareth continued his research career at the Tommys research centre within St Marys hospital, Manchester where he investigated how and why some babies do not grow sufficiently through world leading work in placental physiology.

Gareth joined Chester in 2019 as a lecturer of physiology and is programme leader for BMedSci Medical Science. He has continued to research maternal and fetal health whilst becoming a leading figure within endocrinology with mentions in national media outlets. In addition, Gareth has sat on a number of government sessions and documents calling for greater attention for maternal health.

He remains a huge advocate for student wellbeing and is also a mental health first aider.

Gareth has extensive experience teaching on undergraduate and postgraduate physiology programmes and supervision of undergraduate and postgraduate dissertation students.

He currently teaches across all levels of study within Chester Medical School which includes teaching of both science and clinical sessions.

His broad areas of teaching include cell biology, physiology, pathophysiology/disease and clinical skills. Gareth has specific teaching interests in pregnancy biology, maternal and fetal health and endocrinology.

Gareth’s research focuses on conditions affecting the maternal and fetal environment during pregnancy and how that can influence life post pregnancy.

Erlich, A., G. A. Nye, P. Brownbill, O. E. Jensen & I. L. Chernyavsky (2019) Quantifying the impact of tissue metabolism on solute transport in feto-placental microvascular networks. Interface Focus, 9, 20190021.

Slator, P., R. Aughwane, G. Cade, D. Taylor, A. L. David, R. Lewis, E. Jauniaux, A. Desjardins, L. J. Salomon, A. E. Millischer, V. Tsatsaris, M. Rutherford, E. D. Johnstone, A. Melbourne et al. Placenta Imaging Workshop 2018 report: Multiscale and multimodal approaches. Placenta. Published online Oct 2018. (IF 2.434)

GA Nye, E Ingram, ED Johnstone, OE Jensenm H Schneider, RM Lewis, IL Chernyavsky and P Brownbill. Human placental oxygenation in late gestation: experimental and theoretical approaches. Journal of Physiology. Dec 2018. (IF 4.739)

Acharya G, Aplin J, Brownbill P, Bulmer J, Burton G, Chamley L, Chernyavsky I, Clark A, Collins S, Cottrell E, Dilworth M, Elad D, Filoche M, Hannan N, Heazell AEP, Jensen O, Johnstone ED, Leach L, Lewis R, Morgan T, Myers J, Nye G, Oyen M, Salafia C, Schneider H, O'Tierney-Ginn P. IFPA meeting 2017 workshop report: Clinical placentology, 3D structure-based modeling of placental function, placental bed, and treating placental dysfunction. Placenta. Dec 2017 64 Suppl 1:S4-S8 (IF 2.434)

GK Sakellariou, B McDonagh, H Porter, II Giakoumaki, KE Earl, GA Nye, A Vasilaki, SV Brooks, A Richardson, H Van Remmen, A McArdle and MJ Jackson. Comparison of whole body SOD1 knockout with muscle specific SOD1 knockout mice reveals a role for nerve redox signaling in regulation of degenerative pathways in skeletal muscle. Antioxidants & Redox Signalling. 2017. 28(4):275-95 (IF 7.407)

GA Nye, GK Sakellariou, H Degens, AP Lightfoot. Muscling in on mitochondrial sexual dimorphism; role of mitochondrial dimorphism in skeletal muscle health and disease. Clinical Science (London). Aug 2017. 131(15):1919-22 (IF 5.629)GK Sakellariou, T Pearson, AP Lightfoot, GA Nye, N Wells, II Giakoumaki, RD Griffiths, MJ Jackson and A McArdle. Mitochondrial redox homeostasis regulates organelle integrity and function but is not implicated in muscle aging. Scientific Reports. Sept 2016. 2045-2322 (IF 4.122)

GK Sakellariou, T Pearson, AP Lightfoot, GA Nye, N Wells, II Giakoumaki, RD Griffiths, MJ Jackson and A McArdle. Long-term administration of mitochondria-targeted antioxidant MitoQ exacerbates age‐related oxidative damage, impairs respiration and induces functional deficits in aging skeletal muscle. FASEB J. Nov 2016. 30(11):3771-85 (IF 5.498)

AP Lightfoot, GK Sakellariou, GA Nye, F McArdle, MJ Jackson, RD Griffiths, A McArdle. SS-31 attenuates TNF-α induced cytokine release from C2C12 myotubes, Redox Biology. Dec 2015. 28(1) (IF 7.126)

AP Lightfoot, R McCormick, GA Nye & A McArdle. Mechanisms of skeletal muscle ageing; Avenues for therapeutic intervention, Curr. Op. Pharm. Jun 2014. 16:116-21 (IF 6.313)

BSc (Hons) Physiology, University of Liverpool, 2012

PhD, University of Liverpool, 2016