Dr Mohammed Amali | University of Chester

Senior Lecturer

Dr Amali is a pharmacist and pharmacologist with an interest in drug hypersensitivity reactions and the development of drugs from natural products, with the aim of discovering novel molecules of therapeutic benefit. A senior lecturer in Pharmacology he also serves as the programme leader for the BSc pharmacology programme.

Dr Mohammed Amali obtained his Bachelor of Pharmacy (BPharm) and MSc in Pharmacology from the University of Jos and OAU respectively both in Nigeria. He completed his PhD at the University of Liverpool in 2015, and his thesis focused on characterizing drug hypersensitivity reactions that occur due to administration of beta-lactam antibiotics in patients with cystic fibrosis.

Dr Amali has garnered extensive experience from within the healthcare and education sectors as a pharmacist and an academic. His teaching and research experience spans over fifteen (15) years from the College of Health Sciences to the Faculty of Pharmaceutical Sciences, University of Ilorin.

His research interests include drug allergy but has focused more recently on the development of drugs from natural products, with the aim of discovering novel molecules of therapeutic benefit that will contribute to current patient management strategies. Dr Amali joined the University of Chester Medical School in December 2022 as a Senior Lecturer and a Programme leader for BSc Pharmacology.

My recent research interests include drug allergy with the aim of an expanded comprehension of the immune responses underlying these drug-specific reactions. Additionally, I have focused on the development of drugs from natural products, with the aim of discovering novel molecules of therapeutic benefit.

Bilqis Abiola Lawal, Yusuf Oloruntoyin Ayipo, Abisola Oyindamola Adekunle, Mohammed Otuofu Amali, Umar Muhammad Badeggi, Waleed A. Alananzeh, Mohd Nizam Mordi (2023) Phytoconstituents of Datura metel extract improved motor coordination in haloperidol-induced cataleptic mice: Dual-target molecular docking and behavioural studies. Journal of Ethnopharmacology Vol. 300 115753.

Kola-Mustapha AD, Amali MO, Atunwa SA, Ishola I, Farayola LO, Adeyeye MC. (2022) Beneficial effects of a polyherbal formulation in the management of sickle cell disease. Am J Pharmacother Pharm Sci 1;6.

Amali, M., Atunwa, S., Omotesho, Q., Oyedotun, E., & Olapade, A. (2020). Assessment of anxiolytic potential and acute toxicity study of Combretum micranthum G. Don. leaves (Combretaceae). Journal of Medicinal Plants for Economic Development, 4(1).

Tella, A.C., Eliagwu, S.E., Amali, M., Kola Mustapha, A. T., Olatunji, S. J., Ishola, F., Adimula, V. O., Oluwafemi, O. S. (2020) Synthesis and characterization of amino and cyano-functionalized zinc-terephthalate metal–organic frameworks for loading of piroxicam drug. Chem. Pap. 74, 2287–2296.

Mohammed O. Amali, Monday O. Ogese, Sheriff L. Ojulari (2019) Current Methods in the characterization of immune mechanisms Involved in the elicitation of drug hypersensitivity reactions. J. Pharm. Res. Dev. & Pract., 3(1): 9-26 ISSN: 2579 – 0455

Mohammed O. Amali, Soliu A. Atunwa, Medinat O. Aiyelero, Sukurat O. Usman, Akeem I. Olapade, Eniola O. Oyedotun, and Quadri A. Omotesho. (2019) Acute toxicity study and evaluation of the anxiolytic activity of the Ethanol Leaf Extract of Bryophyllum Pinnatum (Kurz) in Mice. J. Pharm. Res. Dev. & Pract. 3 (1): 27-35 ISSN: 2579 – 0455

S.O. Ayetoro, M. O. Amali, A. O. Olagunju, E.O. Sanya, K.A. Laiyemo, M.J. (2018) Evaluation of adverse drug reactions (ADRs) among in-patients admitted into the adult medical wards of a tertiary hospital in Nigeria. Journal of Pharmaceutical Research Development and Practice 2(1): 9-15.

Njinga NS, Sule MI, Shittu, AO, David MS, Amali, MO, Bolaji AR, Abdullahi ST, Atunwa SA, Hassan, HS, Eniayewu OI (2018) Phytochemical, antibacterial and anticonvulsant activity of the stem bark of Lannea kerstingii Engl. & K. Krause (anacadiaceae). Journal of Pharmacy and Bioresources. 15(2):110-119.

Chris Goldring, Lauren Scarfe, Nathalie Brillant, J. Kumar, Noura Ali, Ahmed Alrumayh, Mohammed Amali, Stephane Barbellion, Vendula Jones, Marije Niemeijer, Sophie Potdevin, Gautier Roussignol, Anatoly Vaganov, Ivana Barbaric, Michael Barrow, John Connell, Francesco Dazzi, Josefina Edsbagge, Neil French, Julie Holder, Claire Hutchinson, David Jones, Tammy Kalber, Cerys Lovatt, Mark Lythgoe, Sara Patel, P. Stephen Patrick, Jacqueline Piner, Jens Reinhardt, Emanuele Ricci, James Sidaway, Glyn Stacey, Philip Starkey Lewis, Gareth Sullivan, Arthur Taylor, Bettina Wilm, Harish Poptani, Patricia Murray, B. Park, and Neal Burton. (2017) Pre-clinical imaging methods for assessing the safety and efficacy of regenerative medicine therapies. Nature Regenerative Medicine. 2:28; doi:10.1038/s41536-017-0029-9

Amali, M. O., Jenkins, R. E., Meng, X., Faulkner, L., Whitaker, P., Peckham, D., Park, B. K., & Naisbitt, D. J. (2017). Assessment of antipiperacillin IgG binding to structurally related drug protein adducts. Chemical Research in Toxicology, 30(12), 2097.

Amali M. O, Sullivan A, Jenkins RE, Farrell J, Meng X, Faulkner L, Whitaker P, Peckham D, Kevin Park B, Naisbitt DJ. (2017) Detection of drug-responsive B lymphocytes and antidrug IgG in patients with β-lactam hypersensitivity. Allergy; 72:896–907.

Njan A.A., Amali, M.O., Olatunji L.O. and Olorundare O.E. (2014) An Overview of the Ethno-Pharmacological Potentials of Moringa Oleifera Lam, “The Miracle Tree”. Arch. Bas. App. Med. 2:135 -145.

Amali, M.O., Bello, M.K., Olatunji, L.O., Salawu, O., Olorundare, O.E. (2012) “Analgesic and anti-Inflammatory activities of ethanolic extract of the stem bark of Kigelia Africana In Wistar albino mice and rats.” Nig. Journ. Pharm. Sci.: 11:13-24.

PhD Pharmacology, University of Liverpool, UK, 2015.
MSc Pharmacology, Obafemi Awolowo University, Nigeria 2010.
Bachelor pf Pharmacy (BPharm), University of Jos Nigeria, 2003.