Dr Ruth Taylor | University of Chester

Lecturer

Ruth joined Chester Medical School in September 2022. Prior to joining the University of Chester, Ruth has been involved in teaching online modules focusing on Neuroscience and the biological aspects of Psychology with a specific relation to Mental Health and has ten years postdoctoral research experience within the Neuroscience field.

Ruth has always enjoyed figuring out how things work, however, she finds the brain particularly fascinating. She started her career studying Physiology at UCL, where she started to specialise in the brain. She then continued her training, studying the modulation of ion channels during her PhD, and becoming interested in the physiological and cellular basis of learning and memory. She then worked as a postdoctoral researcher at the University of Oxford where she developed novel optical and electrophysiological approaches to investigate synaptic plasticity. Following this, she moved to King’s College London where she investigated the use of stem cell derived neurons as a cellular model for autism spectrum disorder.

Ruth has experience of teaching postgraduate Neuroscience and supervision of undergraduate and postgraduate dissertation students within the laboratory environment. Currently she is involved in teaching on the MSc in Psychiatry.

Shum, L. Dutan, E. Annuario, K. Warre-Cornish, S.E. Taylor, R.D. Taylor, L.C. Andreae, N.J. Buckley, J. Price, S. Bhattacharyya, D.P. Srivastava

Δ9-tetrahydrocannabinol and 2-AG decreases neurite outgrowth and differentially affects ERK1/2 and Akt signaling in hiPSC-derived cortical neurons. Molecular and Cellular Neuroscience. 2020 Mar; 103: 103463

R.D.T. Taylor, M. Heine, N.J. Emptage and L.C. Andreae

Neuronal receptors display cytoskeleton-independent directed motion on the plasma membrane. iScience. 2018 Dec 21; 10: 234-244

Taylor, R.D.T. Taylor, J. Price and L.C. Andreae

Single-molecule FISH reveals human SHANK3 mRNA expression varies during development and in autism-associated SHANK3 heterozygosity. Stem Cell Res Ther. 2018 Jul 31;9(1):206

Kathuria, P. Nowosiad, R. Jagasia, S. Aigner, R.D.T. Taylor, L. C. Andreae, W. Luchessi, D. P. Srivastava and J. Price

Stem Cell-derived neurons from autistic individuals with SHANK3 mutation show morphogenetic abnormalities during early development. Mol Psychiatry. 2018 Mar;23(3):735-746

G.W. Anderson, P.J. Deans, R.D.T. Taylor, P. Raval, D. Chen, H. Lowder, S. Murkerji, L.C. Andreae, B.P. Williams and D.P. Srivastava

Characterisation of neurons derived from a cortical human neural stem cell lineCTX0E16. Stem Cell Res. Ther. 6(1): 149 (2015)

R.D.T. Taylor*, M.G. Madsen*, M. Krause, M. Sampedro-Castañeda, M. Stocker and P.Pedarzani

Pituitary adenylate cyclase-activating polypeptide (PACAP) inhibits the slow afterhyperpolarizing current sIAHP in CA1 pyramidal neurons by activating multiple signaling pathways. Hippocampus 24(1): 32-43 (2014)

M.N. Stanton-Humphreys*, R.D.T. Taylor*, C. McDougall, M.L. Hart, C.T.A. Brown, N.J. Emptage and S.J. Conway

Wavelength-orthogonal photorelease of neurotransmitters in vitro. Chemical Communications 48(5): 617-772 (2012).

McGuinness, C.Taylor, R.D.T. Taylor, C. Yau, T. Langenhan, M. L. Hart, P.W. Tynan, H. Christian, P. Donnelly and N.J. Emptage

Presynaptic NMDARs in the hippocampus facilitate transmitter release at theta frequency. Neuron 68:1109-27 (2010).

V.M. Burlakov, R.D.T. Taylor, J. Koerner and N.J. Emptage

Analysis of microscopic parameters of single particle trajectories in neurons. Biophys J., 99(5): 1368-76 (2010).

Strobaek, C. Hougaard, T. H. Johansen, U. S. Sorensen, E. O. Nielsen, K. S. Nielsen, R.D.T. Taylor, P. Pedarzani and P. Christophersen

Inhibitory gating modulation of small conductance Ca2+-activated K+ channels by the synthetic compound NS8593 reduces IAHP in hippocampal CA1 neurons. Mol. Pharm., 70: 1171-1182 (2006).

PhD Physiology, University of London (UCL), 2008

BSc (Hons) Physiology, University of London (UCL), 2003