Biomedical Science MSc

• The nature of research; scientific methods of enquiry, pure versus applied ways of problem solving. The building blocks of scientific research: types of research (analytical, descriptive, experimental, and qualitative), scientific parlance (hypothesis, concepts, operational definitions, and dependent/independent variables), sampling procedures, and measurement issues (reliability and validity)

• Research and data collection methods: experimental research (developing hypotheses, variables, control, sample selection, design, validity); descriptive research (questionnaires, correlational studies); qualitative research and methods of obtaining qualitative data and analysing qualitative data

• Critical appraisal of literature- primary and secondary literature.

•  Importance of evidence based medicine; identifying a topic area, devising specific questions, discovering what is already known (reviewing the literature), determining feasible ways to answer the questions, including consideration of medical and research ethics and confidentiality

The module aims to equip students with the skills required to source and critically analyse relevant research and to apply the theories of evidence based medicine to evaluate relevant concepts in medicine.    

Students will gain an appreciation of aspects of data collection and analysis through lectures , practicals and computer-based sessions covering:

• The sample – collection, transport, storage 
• The assay – assay development, method validation, precision, accuracy, specificity, sensitivity
• Regulatory issues - quality control, SOPs, COSHH, risk assessments 
• Analysis – recording, raw data presentation, statistical analysis using statistics software, summary data and statistical analysis presentation, reference values, interpretation.

 Students will gain experience of a number techniques of relevance to their programme and may include:

• Gel electrophoresis & Western blotting
• Flow cytometry
• Molecular biology techniques (e.g. PCR)
• Immunoassays (e.g. ELISA)
• Histology & microscopy 
• Culturing methods – cell culture, culturing bacteria
• Cell counting methods

The module aims to:

• Develop an understanding of the theories underpinning modern analytical and molecular techniques of relevance to the biomedical and molecular laboratory scientist.
• Develop a critical appreciation of the uses and limitations of a range of analytical and molecular techniques relevant to the biomedical and molecular sciences through practical experience.
• Develop skills in collection, analysis, presentation and interpretation of data. 

This module is focused on the precision medicine approach, looking systematically at a bigger picture of a patient journey from a presentation to NHS with first symptoms to the treatment protocol passing the diagnostic process.

Students will focus on diseases or elements of the pathology or system of relevance to their programme.

The module aims to provide students with an in-depth knowledge of concepts important to our understanding of patient journey in NHS process. The module will focus on the impact of diagnostical procedures on treatment protocol in different pathologies. 

• Institute of Biomedical Science (IBMS)
• Health and Care Professions Council (HCPC)
• IBMS Degree Accreditation
• Biomedical Scientists and Clinical Scientists
• Continuing Professional Development (CPD)
• Healthcare Scientists (NHS Scientist Training Programme, Higher Specialist Scientist Training)
• Careers in Biomedical Science
• Medical Laboratory Accreditation/ United Kingdom Accreditation Service (UKAS)
• Human Tissue Authority (HTA)
• Medicines and Healthcare products Regulatory Agency
  (MHRA)
• Clinical governance
• Laboratory quality management systems
• Laboratory information management systems
• Laboratory automation
• Digital pathology
• Point-of-care testing
• Pathology networks

The module aims to provide students with an in-depth understanding of current issues and developments in Biomedical Science, and of the associated professional and regulatory bodies.

This module will focus on laboratory test performed in blood science laboratories for the diagnosis and management of patients with a variety of conditions.

In this module we will discuss a selection of tests from a variety of laboratories including haematology (routine, transfusion, coagulation and immunophenotyping), molecular biology, immunology, biochemistry and virology. In this module we will discuss the diagnosis of a variety of disorders such as haematological malignancies, non-malignant haematological disorders, Renal Disorders, Liver disease and clinical disorders of lipid metabolism.

The module aims to allow students to develop an understanding of various clinical haematological and biochemical (blood sciences) disorders, and to develop an in-depth knowledge of the laboratory tests performed in the diagnosis and management of such diseases.

Discussion of clinical immunology, including:

• Immune mediated disorders (e.g. mechanism of autoimmunity, hypersensitivity reactions, immunological markers of disease – flow cytometry & ELISA, cytokines)
• Transplantation immunology (HLA polymorphism, HLA function, anti-rejection therapy, graft versus host disease)
• Pathogenesis of infectious disease
• Aspects of infection/host parasite interaction
• Parasitology
• Medical mycology
• Chemotherapy and immunotherapy
• Epidemiology of infectious disease
• Diagnosis of infectious disease

The module aims to allow students to develop an understanding of the immunological processes involved in various aspects of clinical immunology (e.g. autoimmune diseases, hypersensitivity, transplantation) and to develop an in-depth understanding of the interactions between pathogens and the human host.

On completion of the taught modules, students will have developed their knowledge base and attained a high level of competence in the application, analysis and evaluation of theory and practice. This knowledge and critical skills will have been assessed in all previous assignments, thereby providing students with the opportunity to undertake a research project relevant to their taught programme of study. The dissertation subject will be agreed with an appropriate supervisor and the dissertation module leader (Dissertation Co-ordinator). The subject matter may be related to any area of relevance to the area of study.

1.       To provide the student with an opportunity to investigate a research project of direct relevance to the programme of study and his/her personal interests.

2.       To enable the student to draw on and contribute to the development of the growing body of knowledge in the broad biomedical, clinical and medical science fields.

3.       To present the outcomes of the research performed in the form of a research article in a format ready for submission to a suitable journal and as an oral presentation